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LifeSensors - Expression Systems

Careers at LifeSensors


Date Posted: 10.05.09
Scientist (Peptide/Synthetic-organic Chemistry)
The successful candidate will provide a vision for development of novel approaches to bio-organic synthesis and microarray development. In-depth knowledge and expertise in synthetic organic chemistry as well as experience in assay development, protein/peptide purification and modification is highly desirable. The scientist will work closely with members of the team developing screening technologies.

Requirements:

 

 

  • M.S. or Ph.D. in Chemistry with 0 - 2+ years of laboratory experience
  • Extensive experience in synthetic organic chemistry and in chemical modification of proteins and peptides.
  • Prior industry / biotechnology experience is advantageous
     
  • The ability to adapt quickly to change and be able to handle and manage multiple priorities
  • Experience in chemical modification of proteins and peptides or peptide synthesis is a plus
     
  • Proven interpersonal skills with the ability to contribute to a team.
  • Excellent communication, troubleshooting, and organizational skills
Salary and Title will be commensurate with experience and education

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LifeSensors News
 
LifeSensors Launches DiUbiquitin Substrate
A Novel Fluorescent Assay for Ubiquitin Isopeptide Bond Cleavage
MALVERN, PA -- June 29, 2010 --LifeSensors, Inc., a biotechnology company, announces the launch of its novel physiologically relevant diubiquitin substrates for measuring isopeptide bond cleavage (patent applied for). This breakthrough technology, for both basic research and drug discovery targeting the ubiquitin proteasome pathway, offers sensitive, rapid, and robust fluorescent readouts of isopeptidase or de-ubquitylase (DUB) activity.
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LifeSensors

LifeSensors' Gender Sorting Technology Discussed
Feb 9th 2010 | From The Economist online
Dr Butt’s new device is an oestrogen sniffer. It relies on the fact that female embryos produce this hormone in quantity and male ones do not. The sensor uses a fine needle to penetrate both the shell and the allantoic sac of an egg. This sac is a fluid-filled membrane that cushions the embryo and helps it trade carbon dioxide for oxygen from the air. (It is also the membrane that can make peeling a hard-boiled egg such a frustrating affair.)
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LifeSensors

LifeSensors Publishes in Journal of Animal Science
2010 Jan 15.
An estrogen sensor for poultry gender sorting.

Tran HT, Ferrell W, Butt TR.

The need for segregation of poultry based on sex is driven by gender-related differences in growth rate, market age, management practices, and nutritional requirements. Each day, global poultry industry staff would ideally like to determine the gender of >150 million newly hatched birds. Currently, this can be done only manually at the hatchery, which is a virtually impossible undertaking. LifeSensors has developed a facile, rapid, and low cost yeast-based assay that distinguishes male from female embryonated eggs before hatching based on the estrogen level of their allantoic fluid.
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