LifeSensors Launches DiUbiquitin Substrate
A Novel Fluorescent Assay for Ubiquitin Isopeptide Bond Cleavage
MALVERN, PA -- June 29, 2010 --LifeSensors, Inc., a biotechnology company, announces the launch of its novel physiologically relevant diubiquitin substrates for measuring isopeptide bond cleavage (patent applied for). This breakthrough technology, for both basic research and drug discovery targeting the ubiquitin proteasome pathway, offers sensitive, rapid, and robust fluorescent readouts of isopeptidase or de-ubquitylase (DUB) activity.
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LifeSensors' Gender Sorting Technology Discussed
Feb 9th 2010 | From The Economist online
Dr Butt’s new device is an oestrogen sniffer. It relies on the fact that female embryos produce this hormone in quantity and male ones do not. The sensor uses a fine needle to penetrate both the shell and the allantoic sac of an egg. This sac is a fluid-filled membrane that cushions the embryo and helps it trade carbon dioxide for oxygen from the air. (It is also the membrane that can make peeling a hard-boiled egg such a frustrating affair.)
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LifeSensors Publishes in Journal of Animal Science
2010 Jan 15.
An estrogen sensor for poultry gender sorting.
Tran HT, Ferrell W, Butt TR.
The need for segregation of poultry based on sex is driven by gender-related differences in growth rate, market age, management practices, and nutritional requirements. Each day, global poultry industry staff would ideally like to determine the gender of >150 million newly hatched birds. Currently, this can be done only manually at the hatchery, which is a virtually impossible undertaking. LifeSensors has developed a facile, rapid, and low cost yeast-based assay that distinguishes male from female embryonated eggs before hatching based on the estrogen level of their allantoic fluid.
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